Cortisol, Leptin & Lifting

Mike Ratnofsky • November 10, 2025

What Midlife Women Must Know to Train Smarter, Not Harder 


If you’re a woman in your 40s or 50s navigating perimenopause or menopause, you’ve likely experienced the frustrating truth of midlife metabolism: the “eat less, move more” advice doesn’t seem to work anymore.

The real issue? Your hormones — especially cortisol and leptin — may be working against you when it comes to weight loss, energy, and performance. And if you’re doing high-intensity workouts without adjusting your recovery and nutrition strategies, you might be doing more harm than good.

Let’s break it down.

What Is Cortisol — and Why Does It Matter Now More Than Ever?

Cortisol is your body’s primary stress hormone. It’s essential for survival, but when it stays elevated chronically (due to lack of sleep, under-eating, over-training, or life stress), it can cause:

  • Muscle breakdown
  • Fat retention (especially around the belly)
  • Blood sugar dysregulation
  • Suppressed thyroid function


The science:

Women in perimenopause experience a drop in progesterone, which normally acts as a buffer against cortisol. This makes midlife women more sensitive to stress and more prone to cortisol dysregulation.

Reference: Gordon JL et al. Horm Behav. 2015; 76:70–77

What About Leptin?

Leptin is your “satiety hormone” — it tells your brain when you’re full and regulates long-term energy balance. Leptin resistance means your brain doesn’t get the “I’m full” message, leading to overeating, sugar cravings, and stubborn fat storage.


In perimenopausal women, leptin signaling can become blunted due to stress, poor sleep, and low muscle mass — creating a cycle that’s hard to escape without strength training and adequate recovery.

Reference: Riant E et al. Front Endocrinol. 2009; 2(1):5.

So What Can You Do?

Lift Weights (Smartly)

  • Focus on progressive strength training 2–3x/week
  • Avoid excessive cardio or daily HIIT — it may spike cortisol
  • Train with intentional rest between sets and sessions


Recover Like It’s Your Job

  • Walk daily at a Zone 2 pace (helps balance cortisol)
  • Get 7–8 hours of consistent sleep
  • Prioritize post-workout protein + carbs to lower cortisol


Support Leptin & Muscle with Food

  • Eat enough calories (especially protein and healthy fats)
  • Avoid long fasts or skipping meals (spikes cortisol, drops leptin)
  • Focus on real food, timed evenly through the day

Real Talk from the Floor at Strength Lab

At CrossFit Cornelius, we’ve designed Strength Lab to support this exact phase of life. We train smarter — not harder — using:


  • Low-impact strength protocols to reduce cortisol spikes
  • At-home walking plans to support leptin and fat mobilization
  • Nutrition coaching to restore hormonal balance and muscle mass


We see it every week: women who were stuck finally see results — better sleep, lower belly fat, more energy — once they stop overtraining and start strength training for their hormones.


Key Takeaways (Backed by Science)
  • Chronically elevated cortisol breaks down muscle and stores fat
  • Leptin resistance in midlife contributes to hunger and fat retention
  • Strength training and proper recovery improve both hormones
  • Perimenopausal women benefit from low-cortisol strength programming, not more cardio

Join the Founders here at Strength Lab — a program designed by science and built for women.


Classes start Monday, December 1st.


Class Times

Monday & Wednesday at 8:30a and 6:00p

Friday at 8:30a and 5:00p


Click below to reserve your Founders spot:

👉 Reserve Your Spot



By Mike Ratnofsky December 23, 2025
Early in my coaching career, I made a mistake that many coaches make. I ignored my instincts and experience in favor of what I thought would keep people happy. I believed that if I gave members hard workouts every day, they would feel accomplished, challenged, and satisfied. At the time, I thought that was my job. What I did not realize was that I was confusing effort with effectiveness. People trusted me to help improve their fitness, their health, and their confidence. Instead, I was often delivering fatigue. I was chasing intensity instead of outcomes, and I was doing it out of fear. Fear of members getting bored. Fear of people thinking the workout was not hard enough. Fear of losing members if things felt too controlled or too restrained. Looking back, I was not doing anyone justice, including myself as a coach.Hard workouts are easy to design. You can always add more weight, more reps, more rounds, or less rest. You can always make something feel difficult. That part of coaching is not complicated. What is difficult is restraint. Effective training requires saying no more often than yes. It requires understanding that the goal of a workout is not exhaustion, but adaptation. It requires recognizing that different bodies respond differently to stress, and that long term progress depends on managing that stress appropriately. Over time, I learned that my responsibility was not to entertain people or to leave them lying on the floor after every session. My responsibility was to create a long term health and fitness plan for each individual. A roadmap that helped them become stronger, more capable, and more confident over time. That means some days are hard. Truly hard. But they are hard for a reason. They are hard because the stimulus is intentional and aligned with the goal of the day. Other days are simpler, more controlled, and often harder to execute correctly because they require patience and discipline rather than adrenaline. Today, we coach to the intent of the workout, not the ego of the moment. We do not chase weights or reps just to make something feel impressive. We use the program template as a guide. We use the plan to determine appropriate loading, pacing, and volume. The goal is to hit the intended stimulus, not to win the workout. That shift changed everything. Members stopped feeling beat up all the time. Progress became more predictable. Confidence improved because people understood why they were doing what they were doing. Training became something that supported their life instead of competing with it. Effective training takes restraint. It takes patience. It takes the willingness to do what is right instead of what is loud. That is the difference between hard workouts and real coaching. Onward and Upward Mike
By Mike Ratnofsky December 12, 2025
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By Mike Ratnofsky December 10, 2025
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